Individual provider Active NPI

Matthew Ryan Laye, MD

  • Maternal & Fetal Medicine Physician
  • Seneca, SC
National Provider Identifier
1992982623
Registry record updated Aug 20, 2026
On this page

Key facts

NPPES NPI Registry
Primary specialty
Maternal & Fetal Medicine PhysicianTaxonomy code 207VM0101X
License
23546 Issued in SC
Practice address
105B Omni Dr
Seneca, SC 29672-9448
Phone
(864) 482-3157
Fax
(864) 482-3160
NPI assigned
Jan 24, 2008
Last updated
Aug 20, 2026By the provider in NPPES
Sex
Male
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Aug 20, 2026

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Specialty (taxonomy)CodeLicenseStatePrimary
Maternal & Fetal Medicine Physician 207VM0101X 23546 SC Primary

Addresses

Primary practice location

105B Omni Dr
Seneca, SC 29672-9448

Mailing address

300 E McBee Ave FL 4
Greenville, SC 29601-2842

Other practice location 1

853 N Church St
Suite 610
Spartanburg, SC 29303
Phone (864) 560-1600

Other identifiers 2

IdentifierTypeStateIssuer
235463MedicaidSC
5908703MedicaidNC

Electronic endpoints 1

TypeEndpointUseAffiliation
Direct Messaging Address mlaye37335@direct-srhs.et0939.epichosted.com Direct

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in SC
Eligible to order & refer
  • Part B services: Yes
  • Medical equipment: Yes
  • Home health: Yes
  • Power mobility devices: Yes
  • Hospice: Yes
Green means eligible to order or refer.

Enrollment records 1

Enrollment IDStateProvider typePAC IDDetails
I20080508000124 SC Practitioner - Obstetrics/Gynecology 0345329967 Reassigns benefits to 1 organization

Care Compare profile

Medicare Care Compare
Specialty
Obstetrics/Gynecology
Education
University of South Carolina School of Medicine, 2001
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Group practices
Spartanburg Medical CenterGroup PAC ID 3072425297, 1,060 clinicians

Practice addresses (Care Compare)

101 E Wood St
Spartanburg, SC 29303-3040
Phone (864) 560-1576

Merit-based Incentive Payment System (MIPS)

Final score
94.7 of 100Reported as apm
Quality
89.4
Promoting interoperability
100
Improvement activities
40

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

Practice roles

OrganizationSpecialtyStatusNew patients
Spartanburg Medical Center Current Accepting new patients
Spartanburg Medical Center CurrentSince Aug 1, 2008 Accepting new patients
Spartanburg Medical Center CurrentSince Aug 1, 2008 Accepting new patients
Prisma Health University Medical Group PastSince Aug 17, 2026 Accepting new patients
Spartanburg Medical Center Past Accepting new patients

Locations

724 Hyatt St
Gaffney, SC 29341
Phone (864) 488-3980

101 E Wood St
Spartanburg, SC 29303
Phone (864) 560-1915

101 E Wood St
Ste 300
Spartanburg, SC 29303
Phone (864) 560-6554

853 N Church St
Ste 610
Spartanburg, SC 29303
Phone (864) 560-1600

Interoperability endpoints

  • Direct secure messaging: mlaye37335@direct-srhs.et0939.epichosted.com

Organizations & group practices 5

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships, National Provider Directory roles and organizations whose NPPES authorized official is this provider.

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1201132800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1787184000000",
    "number": "1992982623",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "300 E MCBEE AVE FL 4",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296012842"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "105B OMNI DR",
            "city": "SENECA",
            "state": "SC",
            "postal_code": "296729448",
            "telephone_number": "864-482-3157",
            "fax_number": "864-482-3160"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "853 N Church St",
            "address_2": "SUITE 610",
            "address_purpose": "LOCATION",
            "city": "Spartanburg",
            "state": "SC",
            "postal_code": "29303",
            "country_code": "US",
            "telephone_number": "864-560-1600",
            "fax_number": "864-560-0470",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "LAYE",
        "first_name": "MATTHEW",
        "middle_name": "RYAN",
        "credential": "MD",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2008-01-24",
        "last_updated": "2026-08-20",
        "certification_date": "2026-08-20",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207VM0101X",
            "taxonomy_group": "",
            "desc": "Obstetrics & Gynecology, Maternal & Fetal Medicine",
            "state": "SC",
            "license": "23546",
            "primary": true
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "235463",
            "state": "SC"
        },
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "5908703",
            "state": "NC"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "mlaye37335@direct-srhs.et0939.epichosted.com",
            "affiliation": "N",
            "use": "DIRECT",
            "useDescription": "Direct",
            "contentType": "OTHER",
            "contentTypeDescription": "Other",
            "contentOtherDescription": "mlaye37335@direct-srhs.et0939.epichosted.com",
            "address_1": "853 N Church St",
            "address_2": "SUITE 610",
            "city": "Spartanburg",
            "state": "SC",
            "country_code": "US",
            "postal_code": "29303",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Seneca, SC

Sources for this page

Verify at the official NPI Registry.