Individual provider Active NPI

Mark Louis Wess, M.D.

  • Internal Medicine Physician
  • Greenville, SC
National Provider Identifier
1861440042
Registry record updated Mar 25, 2026
On this page

Key facts

NPPES NPI Registry
Primary specialty
Internal Medicine PhysicianTaxonomy code 207R00000X
License
35155 Issued in SC
Practice address
3516 Highway 153
Greenville, SC 29611-7553
Phone
(864) 729-6626
Fax
(855) 617-4425
NPI assigned
May 4, 2006
Last updated
Mar 25, 2026By the provider in NPPES
Sex
Male
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Mar 25, 2026

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Specialty (taxonomy)CodeLicenseStatePrimary
Internal Medicine Physician 207R00000X 35155 SC Primary

Addresses

Primary practice location

3516 Highway 153
Greenville, SC 29611-7553

Mailing address

3516 Highway 153
Greenville, SC 29611-7553
Phone (864) 729-6626

Other identifiers 1

IdentifierTypeStateIssuer
351559MedicaidSC

Electronic endpoints 1

TypeEndpointUseAffiliation
Direct Messaging Address mark.wess.2@29601.direct.athenahealth.com

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in SC
Eligible to order & refer
  • Part B services: Yes
  • Medical equipment: Yes
  • Home health: Yes
  • Power mobility devices: Yes
  • Hospice: Yes
Green means eligible to order or refer.

Enrollment records 1

Enrollment IDStateProvider typePAC IDDetails
I20130116000012 SC Practitioner - Internal Medicine 7719906668 Reassigns benefits to 1 organization

Care Compare profile

Medicare Care Compare
Specialty
Internal Medicine
Education
University of Cincinnati College of Medicine, 1989
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Telehealth
Offers telehealth services
Group practices

Practice addresses (Care Compare)

108 Hwy 28 Byp
Anderson, SC 29624-3742
Phone (864) 772-8173

3516 Hwy 153
Greenville, SC 29611-7553
Phone (864) 729-6626

Hospital & facility affiliations

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

State licenses

LicenseStateTypeSpecialty
35155SCMDInternal Medicine Physician

Practice roles

OrganizationSpecialtyStatusNew patients
Centerwell Senior Primary Care (SC) PC Internal Medicine CurrentSince Mar 6, 2024 Accepting new patients
Centerwell Senior Primary Care (SC) PC Internal Medicine CurrentSince Mar 6, 2024 Accepting new patients
Centerwell Senior Primary Care (SC) PC Internal Medicine Past Accepting new patients
Centerwell Senior Primary Care SC JV PC Internal Medicine Past Accepting new patients
Centerwell Senior Primary Care (SC) PC Internal Medicine Past Accepting new patients
University of Cincinnati Physicians, Inc. Internal Medicine Past Accepting new patients
University Internal Medicine Associates, Inc. Internal Medicine Past Accepting new patients
University Family Physicians, Inc. Past Accepting new patients

Locations

6101 Waterford District Dr
Ste 200
Miami, FL 33126
Phone (407) 533-6836

4700 Millenia Blvd
Ste 650
Orlando, FL 32839
Phone (407) 533-6837

108 Highway 28 Byp
Anderson, SC 29624
Phone (864) 296-5208

3516 Highway 153
Greenville, SC 29611
Phone (864) 729-6626

Interoperability endpoints

  • Direct secure messaging: mark.wess.1@29601.direct.athenahealth.com
  • Direct secure messaging: mark.wess.2@29601.direct.athenahealth.com
  • Direct secure messaging: mark.wess@centerwell.eclinicaldirectplus.com

Organizations & group practices 8

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships, National Provider Directory roles and organizations whose NPPES authorized official is this provider.

Hospital & facility affiliations 50

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

View all 50

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1146700800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1774396800000",
    "number": "1861440042",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "3516 HIGHWAY 153",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296117553",
            "telephone_number": "864-729-6626",
            "fax_number": "855-617-4425"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "3516 HIGHWAY 153",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296117553",
            "telephone_number": "864-729-6626",
            "fax_number": "855-617-4425"
        }
    ],
    "practiceLocations": [],
    "basic": {
        "last_name": "WESS",
        "first_name": "MARK",
        "middle_name": "LOUIS",
        "credential": "M.D.",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2006-05-04",
        "last_updated": "2026-03-25",
        "certification_date": "2026-03-25",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207R00000X",
            "taxonomy_group": "",
            "desc": "Internal Medicine",
            "state": "SC",
            "license": "35155",
            "primary": true
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "351559",
            "state": "SC"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "mark.wess.2@29601.direct.athenahealth.com",
            "affiliation": "N",
            "endpointDescription": "mark.wess.2@29601.direct.athenahealth.com",
            "address_1": "3516 Highway 153",
            "city": "Greenville",
            "state": "SC",
            "country_code": "US",
            "postal_code": "296117553",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Greenville, SC

Sources for this page

Verify at the official NPI Registry.