NPIMap

Individual provider Active NPI

William James Sayre Sr., M.D.

  • Internal Medicine Physician
  • Lexington, VA
National Provider Identifier
1760478275
Registry record updated Jul 8, 2026
On this page

Key facts

NPPES NPI Registry
Primary specialty
Internal Medicine PhysicianTaxonomy code 207R00000X
License
0101229127 Issued in VA
Practice address
108 Houston St Ste a
Lexington, VA 24450-2455
Phone
(540) 463-2181
Fax
(540) 463-1125
NPI assigned
Sep 21, 2005
Sex
Male
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Jul 8, 2026

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Specialty (taxonomy)CodeLicenseStatePrimary
Internal Medicine Physician 207R00000X 0101229127 VA Primary

Addresses

Primary practice location

108 Houston St Ste a
Lexington, VA 24450-2455

Mailing address

213 S Jefferson St Ste 1006
Roanoke, VA 24011-1713
Phone (540) 224-5516

Other identifiers 5

IdentifierTypeStateIssuer
010206766MedicaidVA
110215754OtherVARAILROAD MEDICARE
144808OtherVASOUTHREN HEALTH SERVICES
140212OtherVAANTHEM
005824931MedicaidVA

Electronic endpoints 1

TypeEndpointUseAffiliation
Direct Messaging Address wsayre23116@direct.carilionclinic.org Direct

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in VA
Eligible to order & refer
  • Part B services
  • Medical equipment
  • Home health
  • Power mobility devices
  • Hospice
Green means eligible to order or refer.

Enrollment records 1

Enrollment IDStateProvider typePAC IDDetails
I20051114001133 VA Practitioner - Internal Medicine 5294754701 Reassigns benefits to 3 organizations

Care Compare profile

Medicare Care Compare
Specialty
Internal Medicine
Education
University of Virginia School of Medicine, 1996
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Group practices
Carilion Healthcare CorporationGroup PAC ID 5890607253, 540 clinicians

Practice addresses (Care Compare)

1 Health Cir
Lexington, VA 24450-2448
Phone (540) 462-1200

108 Houston St
A
Lexington, VA 24450-2455
Phone (540) 463-2181

Hospital & facility affiliations

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

Practice roles

OrganizationSpecialtyStatusNew patients
Carilion Rockbridge Community Hospital CurrentSince Oct 1, 2005 Accepting new patients
Carilion Rockbridge Community Hospital CurrentSince Oct 1, 2005 Accepting new patients
Carilion Healthcare Corporation CurrentSince Mar 1, 2009 Accepting new patients
Carilion Healthcare Corporation CurrentSince Mar 1, 2009 Accepting new patients
Carilion Medical Center Past Accepting new patients
Matrix Occupational Health P.C. Past Accepting new patients

Locations

108 Houston St
Ste A
Lexington, VA 24450
Phone (540) 458-3344

108 Houston St
Lexington, VA 24450
Phone (540) 463-2181

1 Health Cir
Lexington, VA 24450
Phone (540) 458-3300

213 S Jefferson St
Ste 1006
Roanoke, VA 24011
Phone (540) 224-5353

213 S Jefferson St
Ste 625
Roanoke, VA 24011
Phone (540) 224-5677

6415 Peters Creek Rd
Roanoke, VA 24019
Phone (703) 562-2110

Interoperability endpoints

  • Direct secure messaging: wsayre23116@direct.carilionclinic.org

Organizations & group practices 7

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

Hospital & facility affiliations 11

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1127260800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1783468800000",
    "number": "1760478275",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "213 S JEFFERSON ST STE 1006",
            "city": "ROANOKE",
            "state": "VA",
            "postal_code": "240111713",
            "telephone_number": "540-224-5516"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "108 HOUSTON ST STE A",
            "city": "LEXINGTON",
            "state": "VA",
            "postal_code": "244502455",
            "telephone_number": "540-463-2181",
            "fax_number": "540-463-1125"
        }
    ],
    "practiceLocations": [],
    "basic": {
        "last_name": "SAYRE",
        "first_name": "WILLIAM",
        "middle_name": "JAMES",
        "name_suffix": "Sr.",
        "credential": "M.D.",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2005-09-21",
        "last_updated": "2026-07-08",
        "certification_date": "2026-07-08",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207R00000X",
            "taxonomy_group": "",
            "desc": "Internal Medicine",
            "state": "VA",
            "license": "0101229127",
            "primary": true
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "010206766",
            "state": "VA"
        },
        {
            "code": "01",
            "desc": "Other (non-Medicare)",
            "issuer": "RAILROAD MEDICARE",
            "identifier": "110215754",
            "state": "VA"
        },
        {
            "code": "01",
            "desc": "Other (non-Medicare)",
            "issuer": "SOUTHREN HEALTH SERVICES",
            "identifier": "144808",
            "state": "VA"
        },
        {
            "code": "01",
            "desc": "Other (non-Medicare)",
            "issuer": "ANTHEM",
            "identifier": "140212",
            "state": "VA"
        },
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "005824931",
            "state": "VA"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "wsayre23116@direct.carilionclinic.org",
            "affiliation": "N",
            "use": "DIRECT",
            "useDescription": "Direct",
            "contentType": "OTHER",
            "contentTypeDescription": "Other",
            "contentOtherDescription": "wsayre23116@direct.carilionclinic.org",
            "address_1": "108 Houston St",
            "city": "Lexington",
            "state": "VA",
            "country_code": "US",
            "postal_code": "244502455",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Lexington, VA

Sources for this page

Verify at the official NPI Registry.