NPIMap

Individual provider Active NPI

Antoinette Denise Rhynes, MD

  • Family Medicine Physician
  • Greenville, SC
National Provider Identifier
1629272331
Registry record updated Mar 5, 2026
On this page

Key facts

NPPES NPI Registry
Primary specialty
Family Medicine PhysicianTaxonomy code 207Q00000X
License
28840 Issued in SC
Practice address
101 Orchard Park Dr
Greenville, SC 29615-3531
Phone
(864) 729-6606
Fax
(855) 617-4426
NPI assigned
Jun 14, 2007
Last updated
Mar 5, 2026By the provider in NPPES
Sex
Female
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Mar 5, 2026

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Specialty (taxonomy)CodeLicenseStatePrimary
Family Medicine Physician 207Q00000X 28840 SC Primary

Addresses

Primary practice location

101 Orchard Park Dr
Greenville, SC 29615-3531

Mailing address

101 Orchard Park Dr
Greenville, SC 29615-3531
Phone (864) 729-6606

Electronic endpoints 1

TypeEndpointUseAffiliation
Direct Messaging Address antoinette.rhynes.2@29601.direct.athenahealth.com

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in SC
Eligible to order & refer
  • Part B services
  • Medical equipment
  • Home health
  • Power mobility devices
  • Hospice
Green means eligible to order or refer.

Enrollment records 1

Enrollment IDStateProvider typePAC IDDetails
I20090813000033 SC Practitioner - Family Practice 0345394136 Reassigns benefits to 2 organizations

Care Compare profile

Medicare Care Compare
Specialty
Family Practice
Education
Medical University of South Carolina College of Medicine, 2006
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Telehealth
Offers telehealth services
Group practices

Practice addresses (Care Compare)

805 W Wade Hampton Blvd
Suite C
Greer, SC 29650-1311
Phone (864) 655-6615

Hospital & facility affiliations

Procedures performed for Medicare patients

ProcedureNumber of procedures
Removal of skin lesions1-10

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

State licenses

LicenseStateTypeSpecialty
28840SCMDFamily Medicine Physician

Practice roles

OrganizationSpecialtyStatusNew patients
Prisma Health University Medical Group CurrentSince Aug 1, 2009 Accepting new patients
Prisma Health University Medical Group Family Medicine CurrentSince Aug 1, 2009 Accepting new patients
Centerwell Senior Primary Care (SC) PC Family Medicine CurrentSince Sep 1, 2025 Accepting new patients

Locations

6101 Waterford District Dr
Ste 200
Miami, FL 33126
Phone (407) 533-6836

108 Highway 28 Byp
Anderson, SC 29624
Phone (864) 296-5208

210 Freeman Farm Rd
Duncan, SC 29334
Phone (864) 968-5123

500 Squires Pt
Duncan, SC 29334
Phone (864) 433-8980

1 Independence Pt
Ste 212
Greenville, SC 29615
Phone (864) 797-6306

100 Augusta St
Greenville, SC 29601
Phone (864) 455-2600

200 Patewood Dr
Bldg A
Greenville, SC 29615
Phone (864) 454-2604

2A Cleveland Ct
Greenville, SC 29607
Phone (864) 271-7761

701 Grove Rd
Greenville, SC 29605
Phone (864) 454-2030

315 Medical Pkwy
Ste 200
Greer, SC 29650
Phone (864) 797-9550

805 W Wade Hampton Blvd
Ste C
Greer, SC 29650
Phone (864) 655-6615

719A SE Main St
Simpsonville, SC 29681
Phone (864) 967-9000

807 N Main St
Travelers Rst, SC 29690
Phone (864) 834-5132

Interoperability endpoints

  • Direct secure messaging: antoinette.rhynes.1@29601.direct.athenahealth.com
  • Direct secure messaging: antoinette.rhynes.2@29601.direct.athenahealth.com
  • Direct secure messaging: antoinette.rhynes@centerwell.eclinicaldirectplus.com

Organizations & group practices 3

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships, National Provider Directory roles and organizations whose NPPES authorized official is this provider.

Hospital & facility affiliations 59

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

View all 59

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1181779200000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1772668800000",
    "number": "1629272331",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "101 ORCHARD PARK DR",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296153531",
            "telephone_number": "864-729-6606",
            "fax_number": "855-617-4426"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "101 ORCHARD PARK DR",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296153531",
            "telephone_number": "864-729-6606",
            "fax_number": "855-617-4426"
        }
    ],
    "practiceLocations": [],
    "basic": {
        "last_name": "RHYNES",
        "first_name": "ANTOINETTE",
        "middle_name": "DENISE",
        "credential": "MD",
        "sole_proprietor": "NO",
        "sex": "F",
        "enumeration_date": "2007-06-14",
        "last_updated": "2026-03-05",
        "certification_date": "2026-03-05",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207Q00000X",
            "taxonomy_group": "",
            "desc": "Family Medicine",
            "state": "SC",
            "license": "28840",
            "primary": true
        }
    ],
    "identifiers": [],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "antoinette.rhynes.2@29601.direct.athenahealth.com",
            "affiliation": "N",
            "address_1": "101 Orchard Park Dr",
            "city": "Greenville",
            "state": "SC",
            "country_code": "US",
            "postal_code": "296153531",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Greenville, SC

Sources for this page

Verify at the official NPI Registry.