Individual provider Active NPI

Yvonne Luyando Simon, MD

  • Family Medicine Physician
  • Mebane, NC
National Provider Identifier
1558329326
Registry record updated Nov 26, 2025
On this page

Key facts

NPPES NPI Registry
Primary specialty
Family Medicine PhysicianTaxonomy code 207Q00000X
License
39192 Issued in NC
Practice address
919 S Fifth St
Mebane, NC 27302-3240
Phone
(919) 563-2896
Fax
(919) 563-2724
NPI assigned
May 2, 2006
Sex
Female
Sole proprietor
Yes

NPPES NPI Registry

Updated by the provider on Nov 26, 2025

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 2

Specialty (taxonomy)CodeLicenseStatePrimary
Specialist 174400000X 39192 NC
Family Medicine Physician 207Q00000X 39192 NC Primary

Addresses

Primary practice location

919 S Fifth St
Mebane, NC 27302-3240

Mailing address

5221 Paramount Pkwy Ste 220
Morrisville, NC 27560-5490
Phone (984) 215-4111

Other practice location 1

109 Conner Dr
ste 1101
Chapel Hill, NC 27514-7039
Phone (919) 968-4551

Other practice location 2

100 E Dogwood Dr
Mebane, NC 27302-7746
Phone (919) 563-2896

Other identifiers 3

IdentifierTypeStateIssuer
53490OtherNCBLUE CROSS BLUE SHIELD
8953490MedicaidNC
080148262OtherNCUNITED HEALTHCARE

Electronic endpoints 1

TypeEndpointUseAffiliation
Direct Messaging Address yluyando79597@direct.UNC.nchie.net Direct

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in NC
Eligible to order & refer
  • Part B services: Yes
  • Medical equipment: Yes
  • Home health: Yes
  • Power mobility devices: Yes
  • Hospice: Yes
Green means eligible to order or refer.

Enrollment records 1

Enrollment IDStateProvider typePAC IDDetails
I20101207000830 NC Practitioner - Family Practice 7315956646 Reassigns benefits to 2 organizations

Care Compare profile

Medicare Care Compare
Specialty
Family Practice
Education
Columbia University College of Physicians and Surgeons, 1984
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Group practices
Unc Physicians Network LLCGroup PAC ID 5496940546, 985 clinicians

Practice addresses (Care Compare)

100 E Dogwood Dr
Mebane, NC 27302-7746
Phone (919) 563-2896

Hospital & facility affiliations

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

State licenses

LicenseStateTypeSpecialty
39192NCMDFamily Medicine Physician

Practice roles

OrganizationSpecialtyStatusNew patients
Unc Physicians Network, LLC Family Medicine CurrentSince Apr 24, 2017 Accepting new patients
Unc Physicians Network LLC Family Medicine Current Accepting new patients
Duke University Affiliated Physicians, Inc Family Medicine CurrentSince Dec 31, 2010 Accepting new patients
Unc Physicians Network LLC Family Medicine CurrentSince Apr 24, 2017 Accepting new patients
Duke University Affiliated Physicians, Inc. Family Medicine CurrentSince Dec 31, 2010 Accepting new patients
Duke University Affiliated Physicians, Inc. Family Medicine Current Accepting new patients

Locations

940 Martin Luther King Jr Blvd
Chapel Hill, NC 27514
Phone (919) 942-5123

77 Vilcom Cir
Ste 200
Chapel Hill, NC 27514
Phone (919) 521-8159

919 S Fifth St
Mebane, NC 27302
Phone (919) 563-2896

100 E Dogwood Dr
Mebane, NC 27302
Phone (919) 563-2896

2000 Perimeter Park Dr
Ste 200
Morrisville, NC 27560
Phone (800) 594-8624

5221 Paramount Pkwy
Ste 220
Morrisville, NC 27560
Phone (984) 215-4110

Interoperability endpoints

  • Direct secure messaging: yluyando79597@direct.unc.nchie.net

Organizations & group practices 6

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

Hospital & facility affiliations 1

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1146528000000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1764115200000",
    "number": "1558329326",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "5221 PARAMOUNT PKWY STE 220",
            "city": "MORRISVILLE",
            "state": "NC",
            "postal_code": "275605490",
            "telephone_number": "984-215-4111"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "919 S FIFTH ST",
            "city": "MEBANE",
            "state": "NC",
            "postal_code": "273023240",
            "telephone_number": "919-563-2896",
            "fax_number": "919-563-2724"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "109 Conner Dr",
            "address_2": "ste 1101",
            "address_purpose": "LOCATION",
            "city": "Chapel Hill",
            "state": "NC",
            "postal_code": "275147039",
            "country_code": "US",
            "telephone_number": "919-968-4551",
            "fax_number": "919-929-7405",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "100 E Dogwood Dr",
            "address_purpose": "LOCATION",
            "city": "Mebane",
            "state": "NC",
            "postal_code": "273027746",
            "country_code": "US",
            "telephone_number": "919-563-2896",
            "fax_number": "919-563-2724",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "SIMON",
        "first_name": "YVONNE",
        "middle_name": "LUYANDO",
        "credential": "MD",
        "sole_proprietor": "YES",
        "sex": "F",
        "enumeration_date": "2006-05-02",
        "last_updated": "2025-11-26",
        "certification_date": "2025-11-26",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "174400000X",
            "taxonomy_group": "",
            "desc": "Specialist",
            "state": "NC",
            "license": "39192",
            "primary": false
        },
        {
            "code": "207Q00000X",
            "taxonomy_group": "",
            "desc": "Family Medicine",
            "state": "NC",
            "license": "39192",
            "primary": true
        }
    ],
    "identifiers": [
        {
            "code": "01",
            "desc": "Other (non-Medicare)",
            "issuer": "BLUE CROSS BLUE SHIELD",
            "identifier": "53490",
            "state": "NC"
        },
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "8953490",
            "state": "NC"
        },
        {
            "code": "01",
            "desc": "Other (non-Medicare)",
            "issuer": "UNITED HEALTHCARE",
            "identifier": "080148262",
            "state": "NC"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "yluyando79597@direct.UNC.nchie.net",
            "affiliation": "N",
            "use": "DIRECT",
            "useDescription": "Direct",
            "contentType": "OTHER",
            "contentTypeDescription": "Other",
            "contentOtherDescription": "CDA/CCD/TXT",
            "address_1": "100 E Dogwood Dr",
            "city": "Mebane",
            "state": "NC",
            "country_code": "US",
            "postal_code": "273027746",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Mebane, NC

Sources for this page

Verify at the official NPI Registry.