NPIMap

Individual provider Active NPI

Matthew W Karshner, MD

  • Physical Medicine & Rehabilitation Physician
  • Cape Girardeau, MO
National Provider Identifier
1477598142
Registry record updated Apr 2, 2026
On this page

Key facts

NPPES NPI Registry
Primary specialty
Physical Medicine & Rehabilitation PhysicianTaxonomy code 208100000X
License
102275 Issued in MO
Practice address
2126 Independence St
Cape Girardeau, MO 63703
Phone
(573) 986-4404
Fax
(573) 986-4439
NPI assigned
Jun 18, 2006
Sex
Male
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Apr 2, 2026

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 2

Specialty (taxonomy)CodeLicenseStatePrimary
Physical Medicine & Rehabilitation Physician 208100000X 102275 MO Primary
Physical Medicine & Rehabilitation Physician 208100000X 036177987 IL

Addresses

Primary practice location

2126 Independence St
Cape Girardeau, MO 63703

Mailing address

2126 Independence St
Cape Girardeau, MO 63703-5826
Phone (573) 986-4404

Other practice location 1

405 W Jackson St
Carbondale, IL 62901-1462
Phone (618) 549-0721

Other practice location 2

2 S Hospital Dr
Murphysboro, IL 62966-3333
Phone (618) 684-3156

Other practice location 3

201 S 14th St
Herrin, IL 62948-3631
Phone (618) 942-2171

Other identifiers 1

IdentifierTypeStateIssuer
208711903MedicaidMO

Electronic endpoints 3

TypeEndpointUseAffiliation
Direct Messaging Address mkarshner90151@sih.direct-ci.com
Direct Messaging Address mkarshner90151@sih.direct-ci.com
Direct Messaging Address mkarshner90151@sih.direct-ci.com

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in MO, NE, IL3 enrollments
Eligible to order & refer
  • Part B services
  • Medical equipment
  • Home health
  • Power mobility devices
  • Hospice
Green means eligible to order or refer.

Enrollment records 3

Enrollment IDStateProvider typePAC IDDetails
I20040102000157 MO Practitioner - Physical Medicine and Rehabilitation 5991604647 Reassigns benefits to 1 organization
I20250528002057 NE Practitioner - Physical Medicine and Rehabilitation 5991604647 Reassigns benefits to 2 organizations
I20260312001596 IL Practitioner - Physical Medicine and Rehabilitation 5991604647 Reassigns benefits to 1 organization

Care Compare profile

Medicare Care Compare
Specialty
Physical Medicine and Rehabilitation
Education
Ohio State University College of Medicine, 1988
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Group practices
Southern Illinois Medical Services NFP 331 clinicians
Regional West Physicians Clinic 136 clinicians
Madonna Rehabilitation Hospital 92 clinicians

Practice addresses (Care Compare)

201 S 14TH St
Herrin, IL 62948-3631
Phone (618) 942-2171

3911 Ave B
Scottsbluff, NE 69361-4617
Phone (308) 630-2030

5401 S St
Lincoln, NE 68506-2150
Phone (402) 489-7102

Hospital & facility affiliations

  • Bryan Medical Center Hospital, Lincoln, NE, CCN 280003
  • Regional West Medical Center Hospital, Scottsbluff, NE, CCN 280061
  • Medical Center of the Rockies Hospital, Loveland, CO, CCN 060119
  • Bryan Medical Center Inpatient rehabilitation facility, Lincoln, NE, CCN 28T003
  • The Acute Rehab Unit at Regional West Medical Cent Inpatient rehabilitation facility, Scottsbluff, NE, CCN 28T061
  • Herrin Hospital Inpatient rehabilitation facility, Herrin, IL, CCN 14T011
  • Madonna Rehabilitation Hospital Lincoln Inpatient rehabilitation facility, Lincoln, NE, CCN 283025

Merit-based Incentive Payment System (MIPS)

Final score
68.72 of 100Reported as individual
Quality
80
Improvement activities
0
Cost
75.29

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

State licenses

LicenseStateTypeSpecialty
036177987ILMDPhysical Medicine & Rehabilitation Physician
102275MOMDPhysical Medicine & Rehabilitation Physician

Practice roles

OrganizationSpecialtyStatusNew patients
Regional West Physicians Clinic Physical Medicine & Rehabilitation CurrentSince Jan 19, 2026 Accepting new patients
Madonna Rehabilitation Hospital Physical Medicine & Rehabilitation CurrentSince Jun 1, 2025 Accepting new patients
Southern Illinois Medical Services, NFP CurrentSince Mar 2, 2026 Accepting new patients
Southeast Missouri Hospital Physicians, LLC Physical Medicine & Rehabilitation CurrentSince Jan 1, 2007 Accepting new patients
Southeast Hospital Current Accepting new patients
Regional West Physicians Clinic Past Accepting new patients
Madonna Rehabilitation Hospital Past Accepting new patients
Bryan Medical Center Past Accepting new patients

Locations

405 W Jackson St
Carbondale, IL 62901

201 S 14th St
Herrin, IL 62948
Phone (618) 942-2171

2 S Hospital Dr
Murphysboro, IL 62966
Phone (618) 684-3156

2126 Independence St
Cape Girardeau, MO 63703
Phone (573) 986-4411

1701 Lacey St
Cpe Girardeau, MO 63701
Phone (573) 334-4822

5401 South St
Lincoln, NE 68506
Phone (402) 413-3000

17500 Burke St
Omaha, NE 68118
Phone (402) 401-3000

3911 Avenue B
Ste 2300
Scottsbluff, NE 69361
Phone (308) 630-1055

3911 Avenue B
Ste G200
Scottsbluff, NE 69361
Phone (308) 630-1355

Interoperability endpoints

  • Direct secure messaging: mkarshner90151@sih.direct-ci.com
  • FHIR API: https://fhir.madonna.org/R4/open-Prod

Organizations & group practices 20

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

View all 20

Hospital & facility affiliations 12

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1150588800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1775088000000",
    "number": "1477598142",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "2126 INDEPENDENCE ST",
            "city": "CAPE GIRARDEAU",
            "state": "MO",
            "postal_code": "637035826",
            "telephone_number": "573-986-4404",
            "fax_number": "573-986-4439"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "2126 INDEPENDENCE ST",
            "city": "CAPE GIRARDEAU",
            "state": "MO",
            "postal_code": "63703",
            "telephone_number": "573-986-4404",
            "fax_number": "573-986-4439"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "405 W Jackson St",
            "address_purpose": "LOCATION",
            "city": "Carbondale",
            "state": "IL",
            "postal_code": "629011462",
            "country_code": "US",
            "telephone_number": "618-549-0721",
            "fax_number": "618-351-4846",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "2 S Hospital Dr",
            "address_purpose": "LOCATION",
            "city": "Murphysboro",
            "state": "IL",
            "postal_code": "629663333",
            "country_code": "US",
            "telephone_number": "618-684-3156",
            "fax_number": "618-351-4846",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "201 S 14th St",
            "address_purpose": "LOCATION",
            "city": "Herrin",
            "state": "IL",
            "postal_code": "629483631",
            "country_code": "US",
            "telephone_number": "618-942-2171",
            "fax_number": "618-351-4846",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "KARSHNER",
        "first_name": "MATTHEW",
        "middle_name": "W",
        "credential": "MD",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2006-06-18",
        "last_updated": "2026-04-02",
        "certification_date": "2026-04-02",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "208100000X",
            "taxonomy_group": "",
            "desc": "Physical Medicine & Rehabilitation",
            "state": "MO",
            "license": "102275",
            "primary": true
        },
        {
            "code": "208100000X",
            "taxonomy_group": "",
            "desc": "Physical Medicine & Rehabilitation",
            "state": "IL",
            "license": "036177987",
            "primary": false
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "208711903",
            "state": "MO"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "mkarshner90151@sih.direct-ci.com",
            "affiliation": "N",
            "address_1": "201 S 14th St",
            "city": "Herrin",
            "state": "IL",
            "country_code": "US",
            "postal_code": "629483631",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "mkarshner90151@sih.direct-ci.com",
            "affiliation": "N",
            "address_1": "405 W Jackson St",
            "city": "Carbondale",
            "state": "IL",
            "country_code": "US",
            "postal_code": "629011462",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "mkarshner90151@sih.direct-ci.com",
            "affiliation": "N",
            "address_1": "2 S Hospital Dr",
            "city": "Murphysboro",
            "state": "IL",
            "country_code": "US",
            "postal_code": "629663333",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Cape Girardeau, MO

Sources for this page

Verify at the official NPI Registry.