Irene-Margarette Louis Spanos, APRN

Primary specialty

Family Nurse PractitionerTaxonomy code 363LF0000X

License

25245 Issued in SC

Practice address

1676 N Highway 17
Mount Pleasant, SC 29464-3310

Phone

(860) 941-5976

NPI assigned

Aug 18, 2021

Sex

Female

Sole proprietor

No

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Addresses

Medicare fee-for-service enrollment

Enrolled in SC

Eligible to order & refer

• Part B services: Yes
• Medical equipment: Yes
• Home health: Yes
• Power mobility devices: Yes
• Hospice: No

Green means eligible to order or refer.

Enrollment records 1

Specialty

Nurse Practitioner

Education

Other, 2021

Medicare assignment

Accepts the Medicare-approved amount as payment in full

Telehealth

Offers telehealth services

Group practices

Minuteclinic Diagnostic South Carolina LLCGroup PAC ID 8527126861, 113 clinicians

Palmetto Primary Care Physicians LLCGroup PAC ID 4880508068, 148 clinicians

Practice addresses (Care Compare)

Hospital & facility affiliations

• Trident Medical Center Hospital, Charleston, SC, CCN 420079
• Mount Pleasant Hospital Hospital, Mount Pleasant, SC, CCN 420104

Medicare enrollment (NPD)

Enrolled

State licenses

Practice roles

Locations

Interoperability endpoints

• Direct secure messaging: irenemargarette.spanos@ppcp1.eclinicaldirectplus.com

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

• Palmetto Primary Care Physicians, LLC

  • Family Medicine Physician
  • Charleston, SC
  • NPI 1073234928

  SC

  Medicare reassignment Care Compare group NPD
• Minuteclinic Diagnostic South Carolina LLC

  • Family Nurse Practitioner
  • Simpsonville, SC
  • NPI 1447420815

  SC

  Medicare reassignment Care Compare group
• Signify Health Medical Associates, PLLC

  • General Practice Physician
  • Dallas, TX
  • NPI 1750845863

  SC

  Medicare reassignment NPD
• Minuteclinic Primary Care South Carolina LLC

  • Family Nurse Practitioner
  • Simpsonville, SC
  • NPI 1548070071

  SC

  Medicare reassignment
• Palmetto Primary Care Physicians, LLC

  • Family Medicine Physician
  • Daniel Island, SC
  • NPI 1144269929
  NPD
• Palmetto Primary Care Physicians, LLC

  • Family Medicine Physician
  • Summerville, SC
  • NPI 1366123739
  NPD
• Palmetto Primary Care Physicians, LLC

  • Family Medicine Physician
  • Summerville, SC
  • NPI 1265690382
  NPD (past)
• Palmetto Primary Care Physicians, LLC

  • Audiologist
  • Ladson, SC
  • NPI 1982175451
  NPD (past)

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

• Roper St. Francis Mount Pleasant Hospital

  • General Acute Care Hospital
  • Mt Pleasant, SC
  • NPI 1255645644

  Hospital

  Care Compare affiliation
• Trident Medical Center, LLC

  • General Acute Care Hospital
  • Charleston, SC
  • NPI 1366496937

  Hospital

  Care Compare affiliation

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1629244800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1773705600000",
    "number": "1457027682",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "1676 N HIGHWAY 17",
            "city": "MOUNT PLEASANT",
            "state": "SC",
            "postal_code": "294643310",
            "telephone_number": "860-941-5976"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "1676 N HIGHWAY 17",
            "city": "MOUNT PLEASANT",
            "state": "SC",
            "postal_code": "294643310",
            "telephone_number": "860-941-5976"
        }
    ],
    "practiceLocations": [],
    "basic": {
        "last_name": "SPANOS",
        "first_name": "IRENE-MARGARETTE",
        "middle_name": "LOUIS",
        "credential": "APRN",
        "sole_proprietor": "NO",
        "sex": "F",
        "enumeration_date": "2021-08-18",
        "last_updated": "2026-03-17",
        "certification_date": "2026-03-17",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "363LF0000X",
            "taxonomy_group": "",
            "desc": "Nurse Practitioner, Family",
            "state": "SC",
            "license": "25245",
            "primary": true
        }
    ],
    "identifiers": [],
    "endpoints": [],
    "other_names": []
}

• Lucas Drew Southerland, D.C.
• Southern Grace Pain & Regenerative Medicine
• Southern Orthopedics and Sports Medicine, LLC
• Southern Tides Dental
• Karmal Spaeth, L. AC.
• Speak.Eat.Learn. LLC
• Caroline Grace Spence, CF-SLP
• Diana E Spencer, DC
• Brooke Bucholtz Sperduto, LPC
• Spine and Orthopaedic Specialists of South Carolina, PA

• All providers in Mount Pleasant, SC
• Family Nurse Practitioner in South Carolina

• NPPES NPI Registry (CMS): identity, addresses, specialties, licenses, identifiers and endpoints. Last updated by the provider on Mar 17, 2026; self-reported and not verified by CMS. Specialty names from the NUCC taxonomy.
• Medicare enrollment (CMS PECOS): enrollments, PAC IDs and benefit reassignments; Order and Referring.
• Medicare Care Compare (CMS): clinician profile, group practices, facility affiliations, MIPS scores and star ratings.
• National Provider Directory (CMS): practice roles, locations, licenses, networks and endpoints.

Verify at the official NPI Registry.