Active NPI
Cane Jayson Holmes, PA-C
- Physician Assistant
- Greer, SC
On this page
Key facts
NPPES NPI Registry- Primary specialty
- Physician Assistant
- License
- 4492
- Practice address
- 315 Medical Pkwy Ste 100
Greer, SC 29650-2455 - Phone
- (864) 454-7422
- Fax
- (864) 797-9701
- NPI assigned
- Oct 14, 2021
- Sex
- Male
- Sole proprietor
- No
NPPES NPI Registry
Registry information is reported by the provider to CMS and is not verified. About this source
Specialties & licenses 2
| Specialty (taxonomy) | Code | License | State | Primary |
|---|---|---|---|---|
| Physician Assistant | 363A00000X | |||
| Physician Assistant | 363A00000X | 4492 | SC | Primary |
Addresses
Primary practice location
315 Medical Pkwy Ste 100
Greer, SC 29650-2455
Mailing address
300 E McBee Ave FL 4
Greenville, SC 29601-2842
Phone (864) 695-6697
Other practice location 1
1001 Sam Perry Blvd
Fredericksburg, VA 22401-4453
Phone (443) 255-6762
Electronic endpoints 1
| Type | Endpoint | Use | Affiliation |
|---|---|---|---|
| Direct Messaging Address | cane.holmes@continuouscare.com |
Medicare participation
Medicare enrollment files- Medicare fee-for-service enrollment
- Enrolled in SC, MD, DC, VA
- Eligible to order & refer
- Part B services: Yes
- Medical equipment: Yes
- Home health: Yes
- Power mobility devices: Yes
- Hospice: No
Enrollment records 4
Care Compare profile
Medicare Care Compare- Specialty
- Physician Assistant
- Education
- Other, 2022
- Medicare assignment
- Accepts the Medicare-approved amount as payment in full
- Group practices
Practice addresses (Care Compare)
175 Patewood Dr
Greenville, SC 29615-3570
Phone (864) 797-1403
200 Patewood Dr
Suite C100
Greenville, SC 29615-6322
Phone (864) 454-7422
210 Freeman Farm Rd
Duncan, SC 29334-9398
Phone (864) 968-5123
315 Medical Pkwy
Suite 100
Greer, SC 29650-2455
Phone (864) 797-9700
830 S Buncombe Rd
Greer, SC 29650-2400
Phone (864) 455-2455
Hospital & facility affiliations
- Prisma Health Home Health-Upstate
- Prisma Health Patewood Hospital
- Prisma Health Greer Memorial Hospital
Merit-based Incentive Payment System (MIPS)
- Final score
- 81.45 of 100
- Quality
- 67.28
- Promoting interoperability
- 98
- Improvement activities
- 40
- Cost
- 72.57
National Provider Directory
National Provider Directory- Medicare enrollment (NPD)
- Enrolled
- Credentials
- Physician Assistant
State licenses
| License | State | Type | Specialty |
|---|---|---|---|
| 4492 | SC | MD | Speech-Language Pathologist |
Practice roles
| Organization | Specialty | Status | New patients |
|---|---|---|---|
| Luminis Health Medical Group, LLC | Current | Accepting new patients | |
| Luminis Health Medical Group, LLC | Current | Accepting new patients | |
| Luminis Health Medical Group, LLC | Current | Accepting new patients | |
| Prisma Health University Medical Group | Current | Accepting new patients | |
| Prisma Health University Medical Group | Current | Accepting new patients |
Locations
2000 Medical Pkwy
Ste 409
Annapolis, MD 21401
Phone (443) 481-5136
2003 Medical Pkwy
Ste 301
Annapolis, MD 21401
Phone (443) 481-3366
2000 Medical Pkwy
Ste 101
Annapolis, MD 21401
Phone (410) 295-8900
4175 N Hanson Ct
Ste 201
Bowie, MD 20716
Phone (443) 481-1199
1630 Main St
Ste 213
Chester, MD 21619
Phone (443) 481-5300
210 Freeman Farm Rd
Duncan, SC 29334
Phone (864) 968-5123
300 E McBee Ave
Fl 4
Greenville, SC 29601
Phone (864) 522-8615
315 Medical Pkwy
Ste 100
Greer, SC 29650
Phone (864) 454-7422
Interoperability endpoints
- cholmes165195@direct.aahs.org
- cholmes862746@direct.ghs.myhfn.org
Organizations & group practices 9
Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.
-
- Family Medicine Physician
- Greenville, SC
- NPI 1295763217
-
- Emergency Medicine Physician
- Myrtle Beach, SC
- NPI 1861430555
-
- Family Medicine Physician
- Fredericksburg, VA
- NPI 1811726698
-
- Maternal & Fetal Medicine Physician
- Annapolis, MD
- NPI 1073580205
-
- Gynecology Physician
- Greer, SC
- NPI 1003619313
-
- Family Medicine Physician
- Pasadena, MD
- NPI 1063837490
-
- Internal Medicine Physician
- Largo, MD
- NPI 1316372931
-
- Internal Medicine Physician
- Bowie, MD
- NPI 1720835010
Hospital & facility affiliations 10
Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.
-
- General Acute Care Hospital
- Greenville, SC
- NPI 1033664909
-
- General Acute Care Hospital
- Greenville, SC
- NPI 1124574223
-
- General Acute Care Hospital
- Greenville, SC
- NPI 1144775032
-
- General Acute Care Hospital
- Greenville, SC
- NPI 1144914607
-
- Home Health Agency
- Greenville, SC
- NPI 1538615653
-
- General Acute Care Hospital
- Spartanburg, SC
- NPI 1629432869
-
- General Acute Care Hospital
- Greenville, SC
- NPI 1730804246
-
- General Acute Care Hospital
- Greer, SC
- NPI 1821760430
-
- General Acute Care Hospital
- Greer, SC
- NPI 1982150009
NPI Registry JSON
The complete NPPES record for this NPI in the NPI Registry API format.
{
"created_epoch": "1634169600000",
"enumeration_type": "NPI-1",
"last_updated_epoch": "1754956800000",
"number": "1447913611",
"addresses": [
{
"country_code": "US",
"country_name": "United States",
"address_purpose": "MAILING",
"address_type": "DOM",
"address_1": "300 E MCBEE AVE FL 4",
"city": "GREENVILLE",
"state": "SC",
"postal_code": "296012842",
"telephone_number": "864-695-6697"
},
{
"country_code": "US",
"country_name": "United States",
"address_purpose": "LOCATION",
"address_type": "DOM",
"address_1": "315 MEDICAL PKWY STE 100",
"city": "GREER",
"state": "SC",
"postal_code": "296502455",
"telephone_number": "864-454-7422",
"fax_number": "864-797-9701"
}
],
"practiceLocations": [
{
"address_1": "1001 Sam Perry Blvd",
"address_purpose": "LOCATION",
"city": "Fredericksburg",
"state": "VA",
"postal_code": "224014453",
"country_code": "US",
"telephone_number": "443-255-6762",
"country_name": "United States",
"address_type": "DOM"
}
],
"basic": {
"last_name": "HOLMES",
"first_name": "CANE",
"middle_name": "JAYSON",
"name_prefix": "Mr.",
"credential": "PA-C",
"sole_proprietor": "NO",
"sex": "M",
"enumeration_date": "2021-10-14",
"last_updated": "2025-08-12",
"certification_date": "2025-08-12",
"status": "A"
},
"taxonomies": [
{
"code": "363A00000X",
"taxonomy_group": "",
"desc": "Physician Assistant",
"state": null,
"license": null,
"primary": false
},
{
"code": "363A00000X",
"taxonomy_group": "",
"desc": "Physician Assistant",
"state": "SC",
"license": "4492",
"primary": true
}
],
"identifiers": [],
"endpoints": [
{
"endpointType": "DIRECT",
"endpointTypeDescription": "Direct Messaging Address",
"endpoint": "cane.holmes@continuouscare.com",
"affiliation": "N",
"address_1": "2655 Northwinds Pkwy",
"city": "Alpharetta",
"state": "GA",
"country_code": "US",
"postal_code": "300092280",
"country_name": "United States",
"address_type": "DOM"
}
],
"other_names": []
}
Other providers in Greer, SC
Sources for this page
- NPPES NPI Registry (CMS): identity, addresses, specialties, licenses, identifiers and endpoints. Last updated by the provider on Aug 12, 2025; self-reported and not verified by CMS. Specialty names from the NUCC taxonomy.
- Medicare enrollment (CMS PECOS): enrollments, PAC IDs and benefit reassignments; Order and Referring.
- Medicare Care Compare (CMS): clinician profile, group practices, facility affiliations, MIPS scores and star ratings.
- National Provider Directory (CMS): practice roles, locations, licenses, networks and endpoints.