Individual provider Active NPI

Cane Jayson Holmes, PA-C

  • Physician Assistant
  • Greer, SC
National Provider Identifier
1447913611
Registry record updated Aug 12, 2025
On this page

Key facts

NPPES NPI Registry
Primary specialty
Physician AssistantTaxonomy code 363A00000X
License
4492 Issued in SC
Practice address
315 Medical Pkwy Ste 100
Greer, SC 29650-2455
Phone
(864) 454-7422
Fax
(864) 797-9701
NPI assigned
Oct 14, 2021
Sex
Male
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Aug 12, 2025

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 2

Specialty (taxonomy)CodeLicenseStatePrimary
Physician Assistant 363A00000X
Physician Assistant 363A00000X 4492 SC Primary

Addresses

Primary practice location

315 Medical Pkwy Ste 100
Greer, SC 29650-2455

Mailing address

300 E McBee Ave FL 4
Greenville, SC 29601-2842
Phone (864) 695-6697

Other practice location 1

1001 Sam Perry Blvd
Fredericksburg, VA 22401-4453
Phone (443) 255-6762

Electronic endpoints 1

TypeEndpointUseAffiliation
Direct Messaging Address cane.holmes@continuouscare.com

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in SC, MD, DC, VA4 enrollments
Eligible to order & refer
  • Part B services: Yes
  • Medical equipment: Yes
  • Home health: Yes
  • Power mobility devices: Yes
  • Hospice: No
Green means eligible to order or refer.

Enrollment records 4

Enrollment IDStateProvider typePAC IDDetails
I20220830000675 SC Practitioner - Physician Assistant 3870977564 Reassigns benefits to 2 organizations
I20231214002307 MD Practitioner - Physician Assistant 3870977564 Reassigns benefits to 1 organization
I20231214002766 DC Practitioner - Physician Assistant 3870977564 Reassigns benefits to 1 organization
I20250318003168 VA Practitioner - Physician Assistant 3870977564 Reassigns benefits to 1 organization

Care Compare profile

Medicare Care Compare
Specialty
Physician Assistant
Education
Other, 2022
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Group practices
Prisma Health University Medical GroupGroup PAC ID 8325950983, 2,467 clinicians

Practice addresses (Care Compare)

175 Patewood Dr
Greenville, SC 29615-3570
Phone (864) 797-1403

200 Patewood Dr
Suite C100
Greenville, SC 29615-6322
Phone (864) 454-7422

210 Freeman Farm Rd
Duncan, SC 29334-9398
Phone (864) 968-5123

315 Medical Pkwy
Suite 100
Greer, SC 29650-2455
Phone (864) 797-9700

830 S Buncombe Rd
Greer, SC 29650-2400
Phone (864) 455-2455

Hospital & facility affiliations

  • Prisma Health Home Health-Upstate Home health agency, Greenville, SC, CCN 427029
  • Prisma Health Patewood Hospital Hospital, Greenville, SC, CCN 420102
  • Prisma Health Greer Memorial Hospital Hospital, Spartanburg, SC, CCN 420033

Merit-based Incentive Payment System (MIPS)

Final score
81.45 of 100Reported as group
Quality
67.28
Promoting interoperability
98
Improvement activities
40
Cost
72.57

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Physician Assistant

State licenses

LicenseStateTypeSpecialty
4492SCMDSpeech-Language Pathologist

Practice roles

OrganizationSpecialtyStatusNew patients
Luminis Health Medical Group, LLC CurrentSince Dec 18, 2023 Accepting new patients
Luminis Health Medical Group, LLC CurrentSince Dec 18, 2023 Accepting new patients
Luminis Health Medical Group, LLC CurrentSince Dec 18, 2023 Accepting new patients
Prisma Health University Medical Group CurrentSince Aug 4, 2025 Accepting new patients
Prisma Health University Medical Group CurrentSince Aug 4, 2025 Accepting new patients

Locations

2000 Medical Pkwy
Ste 409
Annapolis, MD 21401
Phone (443) 481-5136

2003 Medical Pkwy
Ste 301
Annapolis, MD 21401
Phone (443) 481-3366

2000 Medical Pkwy
Ste 101
Annapolis, MD 21401
Phone (410) 295-8900

4175 N Hanson Ct
Ste 201
Bowie, MD 20716
Phone (443) 481-1199

1630 Main St
Ste 213
Chester, MD 21619
Phone (443) 481-5300

210 Freeman Farm Rd
Duncan, SC 29334
Phone (864) 968-5123

300 E McBee Ave
Fl 4
Greenville, SC 29601
Phone (864) 522-8615

315 Medical Pkwy
Ste 100
Greer, SC 29650
Phone (864) 454-7422

Interoperability endpoints

  • Direct secure messaging: cholmes165195@direct.aahs.org
  • Direct secure messaging: cholmes862746@direct.ghs.myhfn.org

Organizations & group practices 9

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

Hospital & facility affiliations 10

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1634169600000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1754956800000",
    "number": "1447913611",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "300 E MCBEE AVE FL 4",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296012842",
            "telephone_number": "864-695-6697"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "315 MEDICAL PKWY STE 100",
            "city": "GREER",
            "state": "SC",
            "postal_code": "296502455",
            "telephone_number": "864-454-7422",
            "fax_number": "864-797-9701"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "1001 Sam Perry Blvd",
            "address_purpose": "LOCATION",
            "city": "Fredericksburg",
            "state": "VA",
            "postal_code": "224014453",
            "country_code": "US",
            "telephone_number": "443-255-6762",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "HOLMES",
        "first_name": "CANE",
        "middle_name": "JAYSON",
        "name_prefix": "Mr.",
        "credential": "PA-C",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2021-10-14",
        "last_updated": "2025-08-12",
        "certification_date": "2025-08-12",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "363A00000X",
            "taxonomy_group": "",
            "desc": "Physician Assistant",
            "state": null,
            "license": null,
            "primary": false
        },
        {
            "code": "363A00000X",
            "taxonomy_group": "",
            "desc": "Physician Assistant",
            "state": "SC",
            "license": "4492",
            "primary": true
        }
    ],
    "identifiers": [],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "cane.holmes@continuouscare.com",
            "affiliation": "N",
            "address_1": "2655 Northwinds Pkwy",
            "city": "Alpharetta",
            "state": "GA",
            "country_code": "US",
            "postal_code": "300092280",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

Other providers in Greer, SC

Sources for this page

Verify at the official NPI Registry.