Clayton Joel Shamblin, M.D.

Primary specialty

Pulmonary Disease PhysicianTaxonomy code 207RP1001X

License

29001 Issued in SC

Practice address

727 SE Main St Ste 120
Simpsonville, SC 29681-3248

Phone

(864) 454-6700

Fax

(864) 454-6705

NPI assigned

Oct 23, 2006

Sex

Male

Sole proprietor

No

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 2

Addresses

Other identifiers 1

Electronic endpoints 1

Medicare fee-for-service enrollment

Enrolled in SC

Eligible to order & refer

• Part B services: Yes
• Medical equipment: Yes
• Home health: Yes
• Power mobility devices: Yes
• Hospice: Yes

Green means eligible to order or refer.

Enrollment records 1

Specialty

Pulmonary DiseaseAlso: Internal Medicine

Education

West Virginia University School of Medicine, 2006

Medicare assignment

Accepts the Medicare-approved amount as payment in full

Telehealth

Offers telehealth services

Group practices

Prisma Health University Medical GroupGroup PAC ID 8325950983, 2,467 clinicians

Practice addresses (Care Compare)

Hospital & facility affiliations

• Interim Healthcare of the Upstate Home health agency, Greenville, SC, CCN 427015
• Heartland Hospice Services - Greenville Hospice, Simpsonville, SC, CCN 421558
• Prisma Health Greenville Memorial Hospital Hospital, Greenville, SC, CCN 420078
• Prisma Health Hillcrest Hospital Hospital, Simpsonville, SC, CCN 420037
• Prisma Health Greer Memorial Hospital Hospital, Spartanburg, SC, CCN 420033
• Prisma Health Baptist Easley Hospital Hospital, Easley, SC, CCN 420015
• Prisma Health Laurens County Hospital Hospital, Clinton, SC, CCN 420038

Medicare enrollment (NPD)

Enrolled

Credentials

Doctor of Medicine

State licenses

Practice roles

Locations

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

• Prisma Health University Medical Group

  • Family Medicine Physician
  • Greenville, SC
  • NPI 1295763217
  Medicare reassignment Care Compare group NPD
• Greenville Health System

  • General Acute Care Hospital
  • Greenville, SC
  • NPI 1568532513
  Medicare reassignment NPD
• Prisma Health Medical Group-Midlands

  • Multi-Specialty Clinic/Center
  • Columbia, SC
  • NPI 1275988321
  Medicare reassignment NPD
• Greenville Health System

  • General Acute Care Hospital
  • Greenville, SC
  • NPI 1225453269
  NPD
• Greenville Health System

  • General Acute Care Hospital
  • Simpsonville, SC
  • NPI 1679992838
  NPD
• Prisma Health Medical Group-Midlands

  • Durable Medical Equipment & Medical Supplies
  • Columbia, SC
  • NPI 1881469856
  NPD
• Prisma Health University Medical Group

  • Gynecology Physician
  • Greer, SC
  • NPI 1003619313
  NPD
• Prisma Health University Medical Group

  • Nurse Practitioner
  • Greenville, SC
  • NPI 1053786483
  NPD

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

• Curo Health Services, LLC

  • Community Based Hospice Care Agency
  • Simpsonville, SC
  • NPI 1588363899
  Care Compare affiliation
• Inspirium Ihc Upstate, LLC

  • Home Health Agency
  • Greenville, SC
  • NPI 1750897609
  Care Compare affiliation
• Prisma Health-Upstate

  • Medically Fragile Infants and Children Day Care
  • Greenville, SC
  • NPI 1093168064

  Hospital

  Care Compare affiliation
• Prisma Health-Upstate

  • General Acute Care Hospital
  • Greenville, SC
  • NPI 1114473212
  Care Compare affiliation
• Prisma Health-Upstate

  • General Acute Care Hospital
  • Greenville, SC
  • NPI 1174079271
  Care Compare affiliation
• Prisma Health-Upstate

  • Radiology Clinic/Center
  • Greenville, SC
  • NPI 1235685330

  Hospital

  Care Compare affiliation
• Prisma Health-Upstate

  • General Acute Care Hospital
  • Clinton, SC
  • NPI 1245786367
  Care Compare affiliation
• Prisma Health-Upstate

  • General Acute Care Hospital
  • Simpsonville, SC
  • NPI 1265988364
  Care Compare affiliation
• Prisma Health-Upstate

  • Sleep Disorder Diagnostic Clinic/Center
  • Greenville, SC
  • NPI 1275086431

  Hospital

  Care Compare affiliation
• Prisma Health-Upstate

  • Multi-Specialty Clinic/Center
  • Greenville, SC
  • NPI 1285180307

  Hospital

  Care Compare affiliation
• Prisma Health-Upstate

  • Clinic/Center
  • Greenville, SC
  • NPI 1316492218

  Hospital

  Care Compare affiliation
• Prisma Health-Upstate

  • General Acute Care Hospital
  • Greenville, SC
  • NPI 1326884982
  Care Compare affiliation

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1161561600000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1765324800000",
    "number": "1306929799",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "300 E MCBEE AVE FL 4",
            "city": "GREENVILLE",
            "state": "SC",
            "postal_code": "296012842",
            "telephone_number": "864-522-8603"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "727 SE MAIN ST STE 120",
            "city": "SIMPSONVILLE",
            "state": "SC",
            "postal_code": "296813248",
            "telephone_number": "864-454-6700",
            "fax_number": "864-454-6705"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "200 Patewood Dr Ste B300",
            "address_purpose": "LOCATION",
            "city": "Greenville",
            "state": "SC",
            "postal_code": "296156338",
            "country_code": "US",
            "telephone_number": "864-454-4200",
            "fax_number": "864-454-4205",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "SHAMBLIN",
        "first_name": "CLAYTON",
        "middle_name": "JOEL",
        "credential": "M.D.",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2006-10-23",
        "last_updated": "2025-12-10",
        "certification_date": "2025-12-10",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207RC0200X",
            "taxonomy_group": "",
            "desc": "Internal Medicine, Critical Care Medicine",
            "state": "SC",
            "license": "29001",
            "primary": false
        },
        {
            "code": "207RP1001X",
            "taxonomy_group": "",
            "desc": "Internal Medicine, Pulmonary Disease",
            "state": "SC",
            "license": "29001",
            "primary": true
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "290018",
            "state": "SC"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "cshamblin7298@direct.ghs.myhfn.org",
            "affiliation": "N",
            "use": "DIRECT",
            "useDescription": "Direct",
            "contentType": "OTHER",
            "contentTypeDescription": "Other",
            "contentOtherDescription": "cshamblin7298@direct.ghs.myhfn.org",
            "address_1": "200 Patewood Dr Ste B300",
            "city": "Greenville",
            "state": "SC",
            "country_code": "US",
            "postal_code": "296156338",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

• Brittany Segriff
• Charmaine Seguro
• Holly Seppala-Williams, REGISTERED NURSE
• Set Counseling
• Brandon Sevener, P.T.
• Michael Courtney Shaw
• Michael Shea
• Allen Hugh Sheffield
• Ihab Mouris Botros Shenouda, M.D.
• Kathleen Jo Sheppard, RN, FNPC

• Pulmonary Disease Physician in Simpsonville, SC
• Providers in Simpsonville, SC by specialty
• Pulmonary Disease Physician in South Carolina

• NPPES NPI Registry (CMS): identity, addresses, specialties, licenses, identifiers and endpoints. Last updated by the provider on Dec 10, 2025; self-reported and not verified by CMS. Specialty names from the NUCC taxonomy.
• Medicare enrollment (CMS PECOS): enrollments, PAC IDs and benefit reassignments; Order and Referring.
• Medicare Care Compare (CMS): clinician profile, group practices, facility affiliations, MIPS scores and star ratings.
• National Provider Directory (CMS): practice roles, locations, licenses, networks and endpoints.

Verify at the official NPI Registry.