Individual provider Active NPI

James W Wilkerson, MD

  • Family Medicine Physician
  • Poplar Bluff, MO
National Provider Identifier
1285612820
Registry record updated Aug 28, 2026
On this page

Key facts

NPPES NPI Registry
Primary specialty
Family Medicine PhysicianTaxonomy code 207Q00000X
License
2000151570 Issued in MO
Practice address
225 Physicians Park Ste 304
Poplar Bluff, MO 63901-3930
Phone
(573) 727-5500
Fax
(573) 399-2646
NPI assigned
Jan 4, 2006
Sex
Male
Sole proprietor
No

NPPES NPI Registry

Updated by the provider on Aug 28, 2026

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Specialty (taxonomy)CodeLicenseStatePrimary
Family Medicine Physician 207Q00000X 2000151570 MO Primary

Addresses

Primary practice location

225 Physicians Park Ste 304
Poplar Bluff, MO 63901-3930

Mailing address

110 S 2ND St
Ellington, MO 63638-9400
Phone (573) 663-2313

Other practice location 1

109 Plum St Ste A
Doniphan, MO 63935-1225
Phone (573) 351-0150

Other practice location 2

109 Plum St Ste C
Doniphan, MO 63935-1225
Phone (573) 351-0150

Other practice location 3

109 Plum St Ste B
Doniphan, MO 63935-1225
Phone (573) 351-0220

Other practice location 4

109 LeRoux St
Doniphan, MO 63935-1038
Phone (573) 996-2136

Other practice location 5

603 E Summit St
Doniphan, MO 63935-1142
Phone (573) 996-3667 ext. 1117

Other practice location 6

202 Allen St
Annapolis, MO 63620-8778
Phone (573) 598-4213

Other practice location 7

3277 US Highway 160 W
Doniphan, MO 63935-5710
Phone (573) 804-9527

Other practice location 8

61 Highway Y
Ellington, MO 63638-7802
Phone (573) 663-2525

Other practice location 9

17959 Main St
Eminence, MO 65466-6375
Phone (573) 226-5505

Other practice location 10

11001 US-160
Harviell, MO 63945
Phone (573) 804-9561

Other practice location 11

220 East Broad Street
Naylor, MO 63953
Phone (573) 399-2311

Other practice location 12

101 E Batten Street
Naylor, MO 63953
Phone (573) 804-1779

Other practice location 13

289 Broadway St
Neelyville, MO 63954-7176
Phone (573) 804-9494

Other practice location 14

1 Hals Plz Ste A
Piedmont, MO 63957-1631
Phone (573) 223-4800

Other practice location 15

315 W Mulberry Ste A
Pilot Knob, MO 63663-7883
Phone (573) 546-0602

Other practice location 16

711 Nickey St
Poplar Bluff, MO 63901-6544
Phone (573) 785-7047 ext. 13040

Other practice location 17

225 Physicians Park Ste 104
Poplar Bluff, MO 63901-3918
Phone (573) 413-4065

Other practice location 18

2879 James Blvd
Poplar Bluff, MO 63901-3395
Phone (573) 712-1610

Other practice location 19

225 Physicians Park Ste 200
Poplar Bluff, MO 63901-3921
Phone (573) 727-5500 ext. 5

Other practice location 20

2210 Barron Rd Ste 120
Poplar Bluff, MO 63901-1922
Phone (573) 785-6536

Other practice location 21

1300 Victory Ln
Poplar Bluff, MO 63901-3300
Phone (573) 785-5566 ext. 17097

Other practice location 22

3001 Warrior Ln Ste A
Poplar Bluff, MO 63901-8685
Phone (573) 785-7453

Other practice location 23

225 Physicians Park Ste 102
Poplar Bluff, MO 63901-3918
Phone (573) 727-5500 ext. 2

Other practice location 24

2879 James Blvd
Poplar Bluff, MO 63901-3395
Phone (573) 609-8800

Other practice location 25

2300 Baugh Ln
Poplar Bluff, MO 63901-2402
Phone (573) 785-3037 ext. 16044

Other practice location 26

405 Main Street
Van Buren, MO 63965
Phone (573) 323-4253

Other practice location 27

18 Viburnum Center Rd
Viburnum, MO 65566-7802
Phone (573) 244-5406

Medicare participation

Medicare enrollment files
Medicare fee-for-service enrollment
Enrolled in MO
Eligible to order & refer
  • Part B services: Yes
  • Medical equipment: Yes
  • Home health: Yes
  • Power mobility devices: Yes
  • Hospice: Yes
Green means eligible to order or refer.

Enrollment records 1

Enrollment IDStateProvider typePAC IDDetails
I20100602000413 MO Practitioner - Family Practice 7618887480 Reassigns benefits to 2 organizations

Care Compare profile

Medicare Care Compare
Specialty
Family Practice
Education
University of Missouri, Columbia School of Medicine, 1995
Medicare assignment
Accepts the Medicare-approved amount as payment in full
Group practices
Saint Francis Medical CenterGroup PAC ID 9931007929, 441 clinicians
Big Springs Medical AssociationGroup PAC ID 6709871007, 53 clinicians
Internal Medicine Associates of Southeast Missouri LLCGroup PAC ID 5991615072, 43 clinicians

Practice addresses (Care Compare)

150 S Mount Auburn Rd
Cape Girardeau, MO 63703-5049

211 Saint Francis Dr
Cape Girardeau, MO 63703-5049

225 Physicians Park
Suite 304
Poplar Bluff, MO 63901-3930
Phone (573) 663-2313

225 Physicians Park
Suite 400
Poplar Bluff, MO 63901-3923
Phone (573) 727-5500

225 Physicians Park Dr
Suite 400
Poplar Bluff, MO 63901-3923

24 S Mount Auburn Rd
Cape Girardeau, MO 63703-5049

Hospital & facility affiliations

  • Amedisys Home Health of Missouri Home health agency, Poplar Bluff, MO, CCN 267151
  • Saint Francis Medical Center Hospital, Cape Girardeau, MO, CCN 260183
  • Poplar Bluff Regional Medical Center Hospital, Poplar Bluff, MO, CCN 260119

Merit-based Incentive Payment System (MIPS)

Final score
67.07 of 100Reported as apm
Quality
85.4
Promoting interoperability
0
Improvement activities
40

National Provider Directory

National Provider Directory
Medicare enrollment (NPD)
Enrolled
Credentials
Doctor of Medicine

State licenses

LicenseStateTypeSpecialty
2000151570MOMDFamily Medicine Physician

Practice roles

OrganizationSpecialtyStatusNew patients
Saint Francis Medical Center Family Medicine CurrentSince Feb 6, 2017 Accepting new patients
Cape Laboratory & Pathology, LC Current Accepting new patients
Saint Francis Medical Center Current Accepting new patients
Big Springs Medical Association CurrentSince Feb 2, 2026 Accepting new patients
Big Springs Medical Association CurrentSince Feb 2, 2026 Accepting new patients
Saint Francis Medical Center CurrentSince Feb 6, 2017 Accepting new patients
Ozarks Medical Center Family Medicine Past Accepting new patients

Locations

211 Saint Francis Dr
Cpe Girardeau, MO 63703
Phone (573) 331-3000

110 S 2nd St
Ellington, MO 63638
Phone (573) 663-2316

225 Physicians Park
Ste 304
Poplar Bluff, MO 63901
Phone (573) 686-2411

225 Physicians Park
Ste 400
Poplar Bluff, MO 63901
Phone (573) 785-7721

686 Lester St
Poplar Bluff, MO 63901
Phone (573) 686-2411

Interoperability endpoints

  • Direct secure messaging: jwilkerson59681@surescripts.sfmc.net

Organizations & group practices 8

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

Hospital & facility affiliations 4

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

NPI Registry JSON

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1136332800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1787875200000",
    "number": "1285612820",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "110 S 2ND ST",
            "city": "ELLINGTON",
            "state": "MO",
            "postal_code": "636389400",
            "telephone_number": "573-663-2313",
            "fax_number": "573-663-2441"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "225 PHYSICIANS PARK STE 304",
            "city": "POPLAR BLUFF",
            "state": "MO",
            "postal_code": "639013930",
            "telephone_number": "573-727-5500",
            "fax_number": "573-399-2646"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "109 Plum St Ste A",
            "address_purpose": "LOCATION",
            "city": "Doniphan",
            "state": "MO",
            "postal_code": "639351225",
            "country_code": "US",
            "telephone_number": "573-351-0150",
            "fax_number": "573-996-2245",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "109 Plum St Ste C",
            "address_purpose": "LOCATION",
            "city": "Doniphan",
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            "postal_code": "639351225",
            "country_code": "US",
            "telephone_number": "573-351-0150",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "109 Plum St Ste B",
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            "state": "MO",
            "postal_code": "639351225",
            "country_code": "US",
            "telephone_number": "573-351-0220",
            "fax_number": "573-996-2246",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "109 LeRoux St",
            "address_purpose": "LOCATION",
            "city": "Doniphan",
            "state": "MO",
            "postal_code": "639351038",
            "country_code": "US",
            "telephone_number": "573-996-2136",
            "fax_number": "573-996-5216",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "603 E Summit St",
            "address_purpose": "LOCATION",
            "city": "Doniphan",
            "state": "MO",
            "postal_code": "639351142",
            "country_code": "US",
            "telephone_number": "573-996-3667 x1117",
            "fax_number": "573-413-4487",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "202 Allen St",
            "address_purpose": "LOCATION",
            "city": "Annapolis",
            "state": "MO",
            "postal_code": "636208778",
            "country_code": "US",
            "telephone_number": "573-598-4213",
            "fax_number": "573-598-1101",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "3277 US Highway 160 W",
            "address_purpose": "LOCATION",
            "city": "Doniphan",
            "state": "MO",
            "postal_code": "639355710",
            "country_code": "US",
            "telephone_number": "573-804-9527",
            "fax_number": "573-804-9536",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "61 Highway Y",
            "address_purpose": "LOCATION",
            "city": "Ellington",
            "state": "MO",
            "postal_code": "636387802",
            "country_code": "US",
            "telephone_number": "573-663-2525",
            "fax_number": "573-663-7844",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "17959 Main St",
            "address_purpose": "LOCATION",
            "city": "Eminence",
            "state": "MO",
            "postal_code": "654666375",
            "country_code": "US",
            "telephone_number": "573-226-5505",
            "fax_number": "573-226-1256",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "11001 US-160",
            "address_purpose": "LOCATION",
            "city": "Harviell",
            "state": "MO",
            "postal_code": "63945",
            "country_code": "US",
            "telephone_number": "573-804-9561",
            "fax_number": "573-804-9581",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "220 East Broad Street",
            "address_purpose": "LOCATION",
            "city": "Naylor",
            "state": "MO",
            "postal_code": "63953",
            "country_code": "US",
            "telephone_number": "573-399-2311",
            "fax_number": "573-399-2076",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "101 E Batten Street",
            "address_purpose": "LOCATION",
            "city": "Naylor",
            "state": "MO",
            "postal_code": "63953",
            "country_code": "US",
            "telephone_number": "573-804-1779",
            "fax_number": "573-804-1789",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "289 Broadway St",
            "address_purpose": "LOCATION",
            "city": "Neelyville",
            "state": "MO",
            "postal_code": "639547176",
            "country_code": "US",
            "telephone_number": "573-804-9494",
            "fax_number": "573-804-9493",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "1 Hals Plz Ste A",
            "address_purpose": "LOCATION",
            "city": "Piedmont",
            "state": "MO",
            "postal_code": "639571631",
            "country_code": "US",
            "telephone_number": "573-223-4800",
            "fax_number": "573-223-7911",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "315 W Mulberry Ste A",
            "address_purpose": "LOCATION",
            "city": "Pilot Knob",
            "state": "MO",
            "postal_code": "636637883",
            "country_code": "US",
            "telephone_number": "573-546-0602",
            "fax_number": "573-546-0546",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "711 Nickey St",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639016544",
            "country_code": "US",
            "telephone_number": "573-785-7047 x13040",
            "fax_number": "573-413-4192",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "225 Physicians Park Ste 104",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639013918",
            "country_code": "US",
            "telephone_number": "573-413-4065",
            "fax_number": "573-354-5013",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "2879 James Blvd",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639013395",
            "country_code": "US",
            "telephone_number": "573-712-1610",
            "fax_number": "573-776-6124",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "225 Physicians Park Ste 200",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639013921",
            "country_code": "US",
            "telephone_number": "573-727-5500 x5",
            "fax_number": "573-313-3684",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "2210 Barron Rd Ste 120",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639011922",
            "country_code": "US",
            "telephone_number": "573-785-6536",
            "fax_number": "573-785-0100",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "1300 Victory Ln",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639013300",
            "country_code": "US",
            "telephone_number": "573-785-5566 x17097",
            "fax_number": "573-413-4194",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "3001 Warrior Ln Ste A",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639018685",
            "country_code": "US",
            "telephone_number": "573-785-7453",
            "fax_number": "573-785-7429",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "225 Physicians Park Ste 102",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639013918",
            "country_code": "US",
            "telephone_number": "573-727-5500 x2",
            "fax_number": "573-413-4609",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "2879 James Blvd",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639013395",
            "country_code": "US",
            "telephone_number": "573-609-8800",
            "fax_number": "573-776-6124",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "2300 Baugh Ln",
            "address_purpose": "LOCATION",
            "city": "Poplar Bluff",
            "state": "MO",
            "postal_code": "639012402",
            "country_code": "US",
            "telephone_number": "573-785-3037 x16044",
            "fax_number": "573-413-4506",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "405 Main Street",
            "address_purpose": "LOCATION",
            "city": "Van Buren",
            "state": "MO",
            "postal_code": "63965",
            "country_code": "US",
            "telephone_number": "573-323-4253",
            "fax_number": "573-323-0154",
            "country_name": "United States",
            "address_type": "DOM"
        },
        {
            "address_1": "18 Viburnum Center Rd",
            "address_purpose": "LOCATION",
            "city": "Viburnum",
            "state": "MO",
            "postal_code": "655667802",
            "country_code": "US",
            "telephone_number": "573-244-5406",
            "fax_number": "573-244-5591",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "WILKERSON",
        "first_name": "JAMES",
        "middle_name": "W",
        "name_prefix": "Dr.",
        "credential": "MD",
        "sole_proprietor": "NO",
        "sex": "M",
        "enumeration_date": "2006-01-04",
        "last_updated": "2026-08-28",
        "certification_date": "2026-08-28",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207Q00000X",
            "taxonomy_group": "",
            "desc": "Family Medicine",
            "state": "MO",
            "license": "2000151570",
            "primary": true
        }
    ],
    "identifiers": [],
    "endpoints": [],
    "other_names": []
}

Other providers in Poplar Bluff, MO

Sources for this page

Verify at the official NPI Registry.