Irene Samuel, M.D.

Primary specialty

Family Medicine PhysicianTaxonomy code 207Q00000X

License

U6796 Issued in TX

Practice address

2220 E League City Pkwy Ste 200
League City, TX 77573-2100

Phone

(281) 523-3110

NPI assigned

May 24, 2016

Last updated

Mar 9, 2026By the provider in NPPES

Sex

Female

Sole proprietor

No

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 2

Addresses

Other names 1

• Irene Varghese Former name

Medicare fee-for-service enrollment

Enrolled in TX

Eligible to order & refer

• Part B services: Yes
• Medical equipment: Yes
• Home health: Yes
• Power mobility devices: Yes
• Hospice: Yes

Green means eligible to order or refer.

Enrollment records 1

Specialty

Family Practice

Education

Other, 2016

Medicare assignment

Accepts the Medicare-approved amount as payment in full

Telehealth

Offers telehealth services

Group practices

TMH Physician Associates PLLCGroup PAC ID 4486711744, 1,881 clinicians

Practice addresses (Care Compare)

Hospital & facility affiliations

• Houston Methodist Clear Lake Hospital Hospital, Nassau Bay, TX, CCN 450709
• Houston Methodist Hospital Hospital, Houston, TX, CCN 450358
• University of Texas Medical Branch Galveston Hospital, Galveston, TX, CCN 450018

Medicare enrollment (NPD)

Enrolled

Credentials

Doctor of Medicine

State licenses

Practice roles

Locations

Interoperability endpoints

• Direct secure messaging: isamuel466960@directhoustonmethodist.org

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships, National Provider Directory roles and organizations whose NPPES authorized official is this provider.

• TMH Physician Associates PLLC

  • Ophthalmology Physician
  • Houston, TX
  • NPI 1275779225

  Family Medicine

  Medicare reassignment Care Compare group NPD
• TMH Physician Associates PLLC

  • Orthopaedic Surgery Physician
  • Spring, TX
  • NPI 1043061351
  NPD
• Methodist Radiology Associates, PLLC

  dba Methodist Breast Imaging

  • Diagnostic Radiology Physician
  • Houston, TX
  • NPI 1427235704
  NPD (past)

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

• Houston Methodist St. John Hospital

  dba Houston Methodist Clear Lake Hospital

  • General Acute Care Hospital
  • Houston, TX
  • NPI 1952723967
  Care Compare affiliation
• The Methodist Hospital

  dba Houston Methodist Hospital

  • General Acute Care Hospital
  • Houston, TX
  • NPI 1548387418
  Care Compare affiliation
• University of Texas Medical Branch at Galveston

  dba University of Texas Medical Branch

  • General Acute Care Hospital
  • Galveston, TX
  • NPI 1548226988
  Care Compare affiliation

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1464048000000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1773014400000",
    "number": "1245687862",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "2220 E LEAGUE CITY PKWY STE 200",
            "city": "LEAGUE CITY",
            "state": "TX",
            "postal_code": "775732100"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "2220 E LEAGUE CITY PKWY STE 200",
            "city": "LEAGUE CITY",
            "state": "TX",
            "postal_code": "775732100",
            "telephone_number": "281-523-3110"
        }
    ],
    "practiceLocations": [
        {
            "address_1": "504 N 40th Ave",
            "address_purpose": "LOCATION",
            "city": "Yakima",
            "state": "WA",
            "postal_code": "989084311",
            "country_code": "US",
            "telephone_number": "509-966-9480",
            "fax_number": "509-225-2704",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "basic": {
        "last_name": "SAMUEL",
        "first_name": "IRENE",
        "credential": "M.D.",
        "sole_proprietor": "NO",
        "sex": "F",
        "enumeration_date": "2016-05-24",
        "last_updated": "2026-03-09",
        "certification_date": "2026-03-09",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "207Q00000X",
            "taxonomy_group": "",
            "desc": "Family Medicine",
            "state": "WA",
            "license": "ML60661168",
            "primary": false
        },
        {
            "code": "207Q00000X",
            "taxonomy_group": "",
            "desc": "Family Medicine",
            "state": "TX",
            "license": "U6796",
            "primary": true
        }
    ],
    "identifiers": [],
    "endpoints": [],
    "other_names": [
        {
            "first_name": "IRENE",
            "last_name": "VARGHESE",
            "code": "1",
            "type": "Former Name"
        }
    ]
}

• Katie D. Salas, PH.D.
• Brittany Salinas, COTA
• Hanaa Sallam, MD, PHD
• Danaja Sallie
• Joachim A Samano, D.D.S.
• Erika Sanchez
• Robert W. Sanders, M.D.
• Brian Joseph Sansalone, D.C.
• Lizbeth Santana-Blaise, NP
• Shelette Santiago, NP

• Family Medicine Physician in League City, TX
• Providers in League City, TX by specialty
• Family Medicine Physician in Texas

• NPPES NPI Registry (CMS): identity, addresses, specialties, licenses, identifiers and endpoints. Last updated by the provider on Mar 9, 2026; self-reported and not verified by CMS. Specialty names from the NUCC taxonomy.
• Medicare enrollment (CMS PECOS): enrollments, PAC IDs and benefit reassignments; Order and Referring.
• Medicare Care Compare (CMS): clinician profile, group practices, facility affiliations, MIPS scores and star ratings.
• National Provider Directory (CMS): practice roles, locations, licenses, networks and endpoints.

Verify at the official NPI Registry.