Annette Iskra Cruz, PA-C

Primary specialty

Medical Physician AssistantTaxonomy code 363AM0700X

License

2614 Issued in SC

Practice address

2085 Henry Tecklenburg Dr Ste 106
Charleston, SC 29414-7711

Phone

(843) 958-2550

Fax

(843) 958-2599

NPI assigned

Sep 26, 2007

Sex

Female

Sole proprietor

No

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 1

Addresses

Other identifiers 1

Electronic endpoints 1

Medicare fee-for-service enrollment

Enrolled in SC

Eligible to order & refer

• Part B services: Yes
• Medical equipment: Yes
• Home health: Yes
• Power mobility devices: Yes
• Hospice: No

Green means eligible to order or refer.

Enrollment records 1

Specialty

Physician Assistant

Education

Other, 2007

Medicare assignment

Accepts the Medicare-approved amount as payment in full

Telehealth

Offers telehealth services

Group practices

Roper Saint Francis Physicians NetworkGroup PAC ID 5193874824, 530 clinicians

Practice addresses (Care Compare)

Hospital & facility affiliations

• Roper-St. Francis Home Health Home health agency, Charleston, SC, CCN 427042
• Mount Pleasant Hospital Hospital, Mount Pleasant, SC, CCN 420104
• Bon Secours-St Francis Xavier Hospital Hospital, Charleston, SC, CCN 420065
• Roper Hospital Hospital, Charleston, SC, CCN 420087

Medicare enrollment (NPD)

Enrolled

Credentials

Physician Assistant

State licenses

Practice roles

Locations

Interoperability endpoints

• Direct secure messaging: annette.cruz@rsfpp.eclinicaldirectplus.com
• Direct secure messaging: acruz1236191@direct.bsmhealth.org

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

• Roper Saint Francis Physicians Network

  dba Roper St. Francis Physician Partners General Surgery

  • Surgery Physician
  • Charleston, SC
  • NPI 1124431606
  Medicare reassignment Care Compare group
• Roper St. Francis Specialty Physicians

  dba Roper St. Francis Physician Partners Bariatric Surgery

  • Surgery Physician
  • Ladson, SC
  • NPI 1528945912

  Physician Assistant

  Medicare reassignment NPD
• University Medical Associates of the Medical University of South Carol

  dba MUSC Physicians

  • Multi-Specialty Clinic/Center
  • Charleston, SC
  • NPI 1043241110
  Medicare reassignment
• Roper Saint Francis Physicians Network

  dba Roper St. Francis Physician Partners OB/GYN

  • Gynecology Physician
  • Mount Pleasant, SC
  • NPI 1306442728
  NPD
• Roper Saint Francis Physicians Network

  dba Roper St. Francis Physician Partners Charleston OB/GYN

  • Obstetrics & Gynecology Physician
  • Charleston, SC
  • NPI 1811857352
  NPD
• University Medical Associates of the Medical University of South Carol

  dba MUSC PHysicians

  • Family Medicine Physician
  • Charleston, SC
  • NPI 1982678496

  Physician Assistant

  NPD
• Richard P Anderson, MD, PC

  • Surgery Physician
  • Springfield, MA
  • NPI 1063607455
  NPD (past)
• Trinity Health of New England Provider Network Organization Inc

  dba Trinity Health Of New England Medical Group

  • Internal Medicine Physician
  • Waterville, ME
  • NPI 1134779531
  NPD (past)

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

• Bon Secours St. Francis Xavier Hospital Inc.

  dba Roper St. Francis Intensivist Services

  • General Acute Care Hospital
  • Charleston, SC
  • NPI 1851361778
  Care Compare affiliation
• Roper Hospital, Inc

  • General Acute Care Hospital
  • Charleston, SC
  • NPI 1962472860
  Care Compare affiliation
• Roper St Francis Ancillary Services

  dba Roper St. Francis Home Health

  • Home Health Agency
  • Ladson, SC
  • NPI 1619947140
  Care Compare affiliation
• Roper St. Francis Mount Pleasant Hospital

  dba Mount Pleasant Hospital

  • General Acute Care Hospital
  • Mount Pleasant, SC
  • NPI 1255645644
  Care Compare affiliation

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1190764800000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1783900800000",
    "number": "1235326976",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "PO BOX 751649",
            "city": "CHARLOTTE",
            "state": "NC",
            "postal_code": "282751649",
            "telephone_number": "888-472-0043",
            "fax_number": "843-724-2440"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "2085 HENRY TECKLENBURG DR STE 106",
            "city": "CHARLESTON",
            "state": "SC",
            "postal_code": "294147711",
            "telephone_number": "843-958-2550",
            "fax_number": "843-958-2599"
        }
    ],
    "practiceLocations": [],
    "basic": {
        "last_name": "CRUZ",
        "first_name": "ANNETTE",
        "middle_name": "ISKRA",
        "name_prefix": "Mrs.",
        "credential": "PA-C",
        "sole_proprietor": "NO",
        "sex": "F",
        "enumeration_date": "2007-09-26",
        "last_updated": "2026-07-13",
        "certification_date": "2026-07-13",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "363AM0700X",
            "taxonomy_group": "",
            "desc": "Physician Assistant, Medical",
            "state": "SC",
            "license": "2614",
            "primary": true
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "2754PA",
            "state": "SC"
        }
    ],
    "endpoints": [
        {
            "endpointType": "DIRECT",
            "endpointTypeDescription": "Direct Messaging Address",
            "endpoint": "Annette.Cruz@rsfpp.eclinicaldirectplus.com",
            "affiliation": "N",
            "endpointDescription": "Document and CCD Exchange",
            "use": "DIRECT",
            "useDescription": "Direct",
            "contentType": "OTHER",
            "contentTypeDescription": "Other",
            "contentOtherDescription": "Patient Care Documents",
            "address_1": "125 Doughty St Ste 280",
            "city": "Charleston",
            "state": "SC",
            "country_code": "US",
            "postal_code": "29403",
            "country_name": "United States",
            "address_type": "DOM"
        }
    ],
    "other_names": []
}

• Samuel Crum, FNP-C
• Arthur Crumbley III, MD
• Faith Charlyn Crumley
• Karen Crummy, LMSW
• Jason J Crumpler, M.D.
• Humberto Alexis Cruz, PSYD
• Jan F Cruz
• William Burke Crymes Jr., M.D.
• Joann Csakany, MD
• Caroline Anna Katherine Csont, CF-SLP

• Medical Physician Assistant in Charleston, SC
• Providers in Charleston, SC by specialty
• Medical Physician Assistant in South Carolina

• NPPES NPI Registry (CMS): identity, addresses, specialties, licenses, identifiers and endpoints. Last updated by the provider on Jul 13, 2026; self-reported and not verified by CMS. Specialty names from the NUCC taxonomy.
• Medicare enrollment (CMS PECOS): enrollments, PAC IDs and benefit reassignments; Order and Referring.
• Medicare Care Compare (CMS): clinician profile, group practices, facility affiliations, MIPS scores and star ratings.
• National Provider Directory (CMS): practice roles, locations, licenses, networks and endpoints.

Verify at the official NPI Registry.