Charles G. Shissias, M.D.

Primary specialty

Neurology PhysicianTaxonomy code 2084N0400X

License

21645 Issued in SC

Practice address

300 Midtown Dr
Beaufort, SC 29906-5200

Phone

(843) 770-0404

Fax

(803) 522-3515

NPI assigned

Aug 11, 2006

Sex

Male

Sole proprietor

Yes

Registry information is reported by the provider to CMS and is not verified. About this source

Specialties & licenses 3

Addresses

Other identifiers 1

Medicare fee-for-service enrollment

Enrolled in SC

Eligible to order & refer

• Part B services: Yes
• Medical equipment: Yes
• Home health: Yes
• Power mobility devices: Yes
• Hospice: Yes

Green means eligible to order or refer.

Enrollment records 1

Specialty

NeurologyAlso: Psychiatry

Education

Medical University of South Carolina College of Medicine, 1994

Medicare assignment

Accepts the Medicare-approved amount as payment in full

Telehealth

Offers telehealth services

Group practices

River Region Psychiatry Associates, LLCGroup PAC ID 1254491012, 118 clinicians

Coastal Inpatient Physicians LLCGroup PAC ID 4688671365, 9 clinicians

Practice addresses (Care Compare)

Hospital & facility affiliations

• Trident Medical Center Hospital, Charleston, SC, CCN 420079

Medicare enrollment (NPD)

Enrolled

Credentials

Doctor of Medicine

State licenses

Practice roles

Locations

Interoperability endpoints

• Direct secure messaging: cshissias22876@directmcleodehealth.org
• Direct secure messaging: charles.shissias@hca5.eclinicaldirectplus.com

Organizations this provider is connected to: Medicare benefit reassignments (the organization bills Medicare for this provider’s services), Care Compare group memberships and National Provider Directory roles.

• Coastal Inpatient Physicians, LLC

  • Internal Medicine Physician
  • Charleston, SC
  • NPI 1215043872

  Neurology, SC

  Medicare reassignment Care Compare group NPD
• River Region Psychiatry Associates LLC

  • Psychiatry Physician
  • Montgomery, AL
  • NPI 1386891497

  Psychiatry, SC

  Medicare reassignment Care Compare group NPD
• McLeod Regional Medical Center of the Pee Dee, Inc

  • Emergency Medical Services (Emergency Medicine) Physician
  • Florence, SC
  • NPI 1154371433

  Neurology, SC

  Medicare reassignment NPD
• McLeod Regional Medical Center of the Pee Dee, Inc

  • Community/Retail Pharmacy
  • Florence, SC
  • NPI 1871775841
  NPD
• South Carolina Neurological Clinic PA

  • Neurology Physician
  • Columbia, SC
  • NPI 1821009077

  Neurology

  NPD (past)
• Trident Medical Center, LLC

  • Psychiatric Hospital Unit
  • Charleston, SC
  • NPI 1124443478
  NPD (past)
• Trident Medical Center, LLC

  • General Acute Care Hospital
  • Charleston, SC
  • NPI 1366496937
  NPD (past)
• Walterboro Community Hospital, Inc.

  • General Acute Care Hospital
  • Walterboro, SC
  • NPI 1376597997
  NPD (past)
• Walterboro Community Hospital, Inc.

  • Psychiatric Hospital Unit
  • Walterboro, SC
  • NPI 1376829952
  NPD (past)

Hospitals and other facilities this clinician is affiliated with according to Medicare Care Compare.

• Trident Medical Center, LLC

  • General Acute Care Hospital
  • Charleston, SC
  • NPI 1366496937

  Hospital

  Care Compare affiliation

The complete NPPES record for this NPI in the NPI Registry API format.

{
    "created_epoch": "1155254400000",
    "enumeration_type": "NPI-1",
    "last_updated_epoch": "1761004800000",
    "number": "1124039334",
    "addresses": [
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "MAILING",
            "address_type": "DOM",
            "address_1": "300 MIDTOWN DR",
            "city": "BEAUFORT",
            "state": "SC",
            "postal_code": "299065200",
            "telephone_number": "843-770-0404",
            "fax_number": "803-522-3515"
        },
        {
            "country_code": "US",
            "country_name": "United States",
            "address_purpose": "LOCATION",
            "address_type": "DOM",
            "address_1": "300 MIDTOWN DR",
            "city": "BEAUFORT",
            "state": "SC",
            "postal_code": "299065200",
            "telephone_number": "843-770-0404",
            "fax_number": "803-522-3515"
        }
    ],
    "practiceLocations": [],
    "basic": {
        "last_name": "SHISSIAS",
        "first_name": "CHARLES",
        "middle_name": "G.",
        "credential": "M.D.",
        "sole_proprietor": "YES",
        "sex": "M",
        "enumeration_date": "2006-08-11",
        "last_updated": "2025-10-21",
        "certification_date": "2025-10-21",
        "status": "A"
    },
    "taxonomies": [
        {
            "code": "2084N0400X",
            "taxonomy_group": "",
            "desc": "Psychiatry & Neurology, Neurology",
            "state": "LA",
            "license": "MD11448R",
            "primary": false
        },
        {
            "code": "2084N0400X",
            "taxonomy_group": "",
            "desc": "Psychiatry & Neurology, Neurology",
            "state": "SC",
            "license": "21645",
            "primary": true
        },
        {
            "code": "2084P0800X",
            "taxonomy_group": "",
            "desc": "Psychiatry & Neurology, Psychiatry",
            "state": "SC",
            "license": "21645",
            "primary": false
        }
    ],
    "identifiers": [
        {
            "code": "05",
            "desc": "MEDICAID",
            "issuer": null,
            "identifier": "216457",
            "state": "SC"
        }
    ],
    "endpoints": [],
    "other_names": []
}

• Shell Point Optical, Inc
• Grace Shelledy, DDS
• Thurman Ray Sherbert, MD
• David P Shervin, ATC
• Jane Shinder
• Marshall Shannon Shook II, MD
• Kristin Shrestha, M.S., CCC-SLP
• Megan Shytle
• Mark Samuel Siegel, M.D.
• Louis C. Sigmund II, DDS

• All providers in Beaufort, SC
• Neurology Physician in South Carolina

• NPPES NPI Registry (CMS): identity, addresses, specialties, licenses, identifiers and endpoints. Last updated by the provider on Oct 21, 2025; self-reported and not verified by CMS. Specialty names from the NUCC taxonomy.
• Medicare enrollment (CMS PECOS): enrollments, PAC IDs and benefit reassignments; Order and Referring.
• Medicare Care Compare (CMS): clinician profile, group practices, facility affiliations, MIPS scores and star ratings.
• National Provider Directory (CMS): practice roles, locations, licenses, networks and endpoints.

Verify at the official NPI Registry.